Daunoxome

 
Generic Name: daunorubicin liposomal

Brands: Daunoxome

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What is the most important information I should know about Daunoxome?

· Daunoxome should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

· Serious side effects have been reported with the use of Daunoxome including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); severe heart damage with prolonged use; decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection); severe nausea, vomiting, diarrhea, and loss of appetite; and others. Talk to your doctor about the possible side effects from treatment with Daunoxome.

 

What is Daunoxome?

· Daunoxome is a cancer (antineoplastic) medication. Daunoxome interferes with the growth of cancer cells and slows their growth and spread in the body.

· Daunoxome is used to treat advanced HIV-associated Kaposi's sarcoma.

· Daunoxome may also be used for purposes other than those listed in this medication guide.

 

Who should not use Daunoxome?

· Do not use Daunoxome without first talking to your doctor if you have     ·kidney disease;     ·liver disease;     ·heart disease;     ·poor bone marrow function;     ·received radiation therapy that encompassed the heart; or     ·previously received treatment with doxorubicin (Adriamycin, Rubex), doxorubicin liposomal (Doxil), daunorubicin (Cerubidine), Daunoxome (Daunoxome), idarubicin (Idamycin), or mitoxantrone (Novantrone).

· The use of Daunoxome may be dangerous if you have any of the conditions listed above.

· Daunoxome is in the FDA pregnancy category D. This means that Daunoxome is known to be harmful to an unborn baby.Do not use Daunoxome without first talking to your doctor if you are pregnant. Discuss with your doctor the appropriate use of birth control during treatment with Daunoxome if necessary.

· Daunoxome passes into breast milk and may harm a nursing baby. Breast-feeding should be avoided during treatment with Daunoxome.

 

How should I use Daunoxome?

· Daunoxome should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

· Your doctor will determine the correct amount and frequency of treatment with Daunoxome depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.

· Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with Daunoxome to monitor progress and side effects.

· Skin accidentally exposed to Daunoxome should be rinsed thoroughly with soap and warm water.

· Your healthcare provider will store Daunoxome as directed by the manufacturer. If you are storing Daunoxome at home, follow the directions provided by your healthcare provider.

 

What happens if I miss a dose?

· Contact your doctor if you miss a dose of Daunoxome.

 

What happens if I overdose?

· If for any reason an overdose of Daunoxome is suspected, seek emergency medical attention or contact your healthcare provider immediately.

· Symptoms of a Daunoxome overdose tend to be similar to side effects caused by the medication, although often more severe.

 

What should I avoid while using Daunoxome?

· Daunoxome can lower the activity of your immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with Daunoxome. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you.

· Skin accidentally exposed to Daunoxome should be rinsed thoroughly with soap and warm water.

 

What are the possible side effects of Daunoxome?

· If you experience any of the following serious side effects from Daunoxome, contact your doctor immediately:     ·an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);     ·decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection);     ·congestive heart failure (difficulty breathing, fluid retention, chest pain);     ·tissue or vein reactions near the site of administration;     ·liver damage (abdominal pain, yellowing of the skin or eyes);     ·nausea, vomiting, diarrhea, or loss of appetite;     ·inflamation or sores inside the mouth, throat, or intestines;     ·numbness or tingling;     ·fever, chills, or other signs of infection; or     ·back pain, flushing, and chest tightness while Daunoxome is being administered.

· Other, less serious side effects may be more likely to occur. Continue taking Daunoxome and talk to your doctor if you experience:     ·temporary hair loss; or     ·red colored urine for 1 or 2 days following a dose.

· Other side effects have also been reported. Discuss with your doctor any side effect that occurs during treatment with Daunoxome.

 

What other drugs will affect Daunoxome?

· Do not use Daunoxome without first talking to your doctor if you have had previous treatment with doxorubicin (Adriamycin, Rubex), doxorubicin liposomal (Doxil), daunorubicin (Cerubidine), Daunoxome (Daunoxome), idarubicin (Idamycin), or mitoxantrone (Novantrone). Because there is a maximum amount of these medications that should be administered to an individual, you may not be able to use Daunoxome.

· Do not receive "live" vaccines during treatment with Daunoxome. Administration of a live vaccine may be dangerous during treatment with Daunoxome.

· Drugs other than those listed here may also interact with Daunoxome. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines, including herbal products, during treatment with Daunoxome.

 

Where can I get more information?

· Your healthcare provider may have additional information about Daunoxome that you may read.

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