E-Pilo-1 - Talk Medical

Generic Name: epinephrine and pilocarpine ophthalmic

Brands: E-Pilo-1, E-Pilo-2, E-Pilo-4, E-Pilo-6, P1E1, P2E1, P3E1, P4E1, P6E1

What is the most important information I should know about E-Pilo-1?

· Contact your doctor immediately if you notice any decrease in vision or an increase in "floaters" in your visual field. Rarely, pilocarpine ophthalmic may cause retinal detachment. Retinal detachment can lead to blind spots, floaters in your visual field, and even blindness. Your doctor will want to check your retina before you use this medication to determine if you have an increased risk of retinal detachment.

· Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

· Apply light pressure to the inside corner of the eye (near the nose) after each drop to prevent the fluid from draining down the tear duct.

· Use caution when driving, operating machinery, or performing other hazardous activities. E-Pilo-1 may cause blurred or decreased night vision. If you experience blurred or decreased vision, avoid these activities.

What is E-Pilo-1?

· Epinephrine ophthalmic reduces congestion in the eye by constricting blood vessels in the eye. It also enlarges the pupil, and it reduces the amount of fluid in the eye in two ways: It reduces the production of fluid inside the eye, and it increases the amount of fluid that drains from the eye.

· Pilocarpine ophthalmic also reduces pressure in the eye by increasing the amount of fluid that drains from the eye. In addition, pilocarpine causes the pupil to become smaller and reduces its response to light or dark conditions.

· Together, epinephrine and pilocarpine are used to lower increased pressure in the eye that may be caused by conditions such as open-angle glaucoma and ocular (eye) hypertension (high pressure).

· E-Pilo-1 is not commercially available in the United States.

· E-Pilo-1 may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before using E-Pilo-1?

· E-Pilo-1 should not be used to treat narrow- or shallow-angle glaucoma.

· Rarely, pilocarpine ophthalmic may cause retinal detachment. Tell your doctor if you have any type of retinal disease, if you have had a retinal tear, if you are nearsighted, or if you have had cataract surgery. These conditions may increase the risk of retinal detachment.

· Before using this medication, tell your doctor if you have ·heart failure, ·high or low blood pressure, ·ever had a heart attack, ·asthma, ·a stomach ulcer or stomach spasms, ·epilepsy, ·hyperthyroidism (an overactive thyroid), ·blockage of your urinary tract or difficulty urinating, or ·Parkinson's disease.

· You may not be able to use E-Pilo-1, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

· If you wear contact lenses, remove them before applying E-Pilo-1. Ask your doctor if contact lenses can be reinserted after application of the medication.

· It is not known whether E-Pilo-1 will be harmful to an unborn baby. Do not use E-Pilo-1 without first talking to your doctor if you are pregnant or could become pregnant during treatment.

· It is not known whether epinephrine and pilocarpine passes into breast milk. Do not use E-Pilo-1 without first talking to your doctor if you are breast-feeding a baby.

How should I use E-Pilo-1?

· Use E-Pilo-1 eye drops exactly as directed by your doctor. If you do not understand these instructions, ask your doctor, pharmacist, or nurse to explain them to you.

· Wash your hands before and after using the eye drops.

· If you wear contact lenses, remove them before applying E-Pilo-1. Ask your doctor if contact lenses can be reinserted after application of the medication.

· To apply the eye drops: ·Tilt the head back slightly and pull down on the lower eyelid. Position the dropper above the eye. Look up and away from the dropper. Squeeze out a drop and close the eye. Apply gentle pressure to the inside corner of the eye (near the nose) for about 1 minute to prevent the liquid from draining down the tear duct. If you are using more than 1 drop in the same eye, repeat the process with about 5 minutes between drops. Repeat the process in the other eye if needed.

· E-Pilo-1 is usually used once or twice a day. Follow your doctor's instructions.

· Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

· Do not use any eye drop that is discolored or has particles in it.

· Store E-Pilo-1 at room temperature away from moisture and heat. Keep the bottle properly capped.

What happens if I miss a dose?

· Apply the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication.

What happens if I overdose?

· The symptoms of an E-Pilo-1 overdose are unknown. Sweating, nausea, vomiting, diarrhea, watering mouth, and tearing eyes may occur. If you suspect an overdose, or if the drops have been ingested, call an emergency room or poison control center for advice.

What should I avoid while using E-Pilo-1?

· Do not touch the dropper to any surface, including your eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in your eye.

· If you wear contact lenses, remove them before applying E-Pilo-1. Ask your doctor if contact lenses can be reinserted after application of the medication.

· Do not use other eye medications during treatment with E-Pilo-1 except under the direction of your doctor.

What are the possible side effects of E-Pilo-1?

· If you experience any of the following serious side effects, stop using E-Pilo-1 and seek emergency medical attention or contact your doctor immediately: ·an allergic reaction (swelling of the lips, face, or tongue; difficulty breathing; shortness of breath; or hives); ·high blood pressure (severe headache, blurred vision, or flushed skin); or ·an irregular or fast heartbeat.

· Other, less serious side effects may be more likely to occur. Continue to use E-Pilo-1 and talk to your doctor if you experience ·burning, stinging, redness, or tearing of the eye; ·blurred vision; ·headache or brow ache; ·dizziness; ·decreased vision in poor light; ·nausea, vomiting, or diarrhea; ·watering mouth; ·sweating; or ·increased urination.

· Colored deposits (spots) on the inner lining of the eyelid or on the surface of the eye may develop during chronic treatment with E-Pilo-1. These deposits are harmless.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect E-Pilo-1?

· Before using this medication, tell your doctor if you are using another eye medication especially if it is a nonsteroidal anti-inflammatory drug (NSAID) such as flurbiprofen (Ocufen), suprofen (Profenal), diclofenac (Voltaren), or ketorolac (Acular).

· Do not use other eye medications during treatment with E-Pilo-1 except under the direction of your doctor.

· Drugs other than those listed here may also interact with E-Pilo-1. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

· Your pharmacist has additional information about E-Pilo-1 written for health professionals that you may read.