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Ogen 2.5

 
Generic Name: estropipate

Brands: Ogen 0.625, Ogen 1.25, Ogen 2.5, Ortho-Est


What is the most important information I should know about Ogen 2.5?

· Ogen 2.5 increases the risk of developing a condition (endometrial hyperplasia) that may lead to cancer of the lining of the uterus. Taking progestins, another hormone drug, with Ogen 2.5 lowers the risk of developing this condition. Therefore, if your uterus has not been removed, your doctor may prescribe a progestin for you to take together with the estrogen. Visit your doctor regularly and report any unusual vaginal bleeding right away.

· Treatment with estrogens long-term may increase the risk of stroke. Because of this risk, you should contact your doctor or healthcare provider to discuss your individual risks and benefits before taking an estrogen long-term. You should also talk to your doctor or healthcare provider on a regular basis (for example, every 3-6 months) about whether you should continue this treatment.

· Have yearly physical exams and examine your breasts for lumps on a monthly basis while taking Ogen 2.5.

· Do not take Ogen 2.5 if you are pregnant.

 

What is Ogen 2.5?

· Ogen 2.5 is a form of estrogen. Estrogen is a female sex hormone necessary for many processes in the body.

· Ogen 2.5 is used to treat symptoms of menopause; deficiency in ovary function (including underdevelopment of female sexual characteristics and some types of infertility); some types of breast cancer in men and in postmenopausal women; degeneration of the vagina and urethra; and prostate cancer. In addition, Ogen 2.5 is used to prevent osteoporosis.

· Ogen 2.5 may also be used for purposes other than those listed in this medication guide.

 

What should I discuss with my healthcare provider before taking take Ogen 2.5?

· Do not take Ogen 2.5 without first talking to your doctor if you have     ·a circulation, bleeding, or blood-clotting disorder;     ·undiagnosed, abnormal vaginal bleeding; or     ·any type of breast, uterine, or hormone-dependent cancer.

· Taking Ogen 2.5 may be dangerous in some cases if you have any of the conditions listed above.

· Before taking Ogen 2.5, tell your doctor if you have     ·high blood pressure, angina, or heart disease;     ·high levels of cholesterol or triglycerides in the blood;     ·liver disease;     ·kidney disease;     ·asthma;     ·epilepsy;     ·migraines;     ·diabetes;     ·depression;     ·gallbladder disease;     ·uterine fibroids; or     ·had a hysterectomy (uterus removed).

· You may not be able to take Ogen 2.5, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

· Ogen 2.5 is in the FDA pregnancy category X. This means that Ogen 2.5 is known to cause birth defects in an unborn baby. Do not take this medication if you are pregnant or could become pregnant during treatment.

· Ogen 2.5 may decrease milk flow and have other effects on milk composition. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.

 

How should I take Ogen 2.5?

· Take this medication exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

· Take each dose with a full glass of water.

· Take Ogen 2.5 with food or milk to lessen stomach upset.

· Try to take each dose at the same time each day. You may be taking it every day, or you may be taking it every day for 3 weeks with 1 week off each month to mimic your body's natural cycle. Follow the directions on your prescription label.

· If you are taking Ogen 2.5 to treat cancer, you may be taking it several times a day in very large doses.

· It is important to take Ogen 2.5 regularly to get the most benefit.

· Have yearly physical exams and examine your breasts for lumps on a monthly basis while taking Ogen 2.5.

· Store Ogen 2.5 at room temperature away from moisture and heat.

 

What happens if I miss a dose?

· Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the misse dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

 

What happens if I overdose?

· An overdose of this medication is unlikely to threaten life. Consult an emergency room or poison control center for advice.

· Symptoms of an Ogen 2.5 overdose include nausea, vomiting, and breakthrough bleeding in females.

 

What should I avoid while taking Ogen 2.5?

· There are no restrictions on food, beverages, or activity while taking Ogen 2.5 unless your doctor directs otherwise.

 

What are the possible side effects of Ogen 2.5?

· Ogen 2.5 increases the risk of developing a condition (endometrial hyperplasia) that may lead to cancer of the lining of the uterus. Taking progestins, another hormone drug, with Ogen 2.5 lowers the risk of developing this condition. Therefore, if your uterus has not been removed, your doctor may prescribe a progestin for you to take together with the estrogen. Visit your doctor regularly and report any unusual vaginal bleeding right away.

· Treatment with estrogens long-term may increase the risk of stroke. Because of this risk, you should contact your doctor or healthcare provider to discuss your individual risks and benefits before taking an estrogen long-term. You should also talk to your doctor or healthcare provider on a regular basis (for example, every 3-6 months) about whether you should continue this treatment.

· If you experience any of the following serious side effects, stop taking Ogen 2.5 and seek emergency medical attention or contact your doctor immediately:     ·an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);     ·a blood clot (pain, redness, and swelling in an arm or leg, shortness of breath, chest pain, headache, blurred vision, or confusion);     ·a lump in a breast; or     ·liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).

· Other, less serious side effects may be more likely to occur. Continue to take Ogen 2.5 and talk to your doctor if you experience     ·decreased appetite, nausea, or vomiting;     ·swollen or tender breasts;     ·acne or skin color changes;     ·decreased sex drive;     ·migraine headaches or dizziness;     ·water retention (swollen hands, feet, or ankles);     ·problems with wearing contact lenses;     ·depression; or     ·changes in your menstrual cycle or breakthrough bleeding.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Ogen 2.5?

· Before taking Ogen 2.5, tell your doctor if you are taking any of the following medicines:     ·an anticoagulant (blood thinner) such as warfarin (Coumadin);     ·a thyroid medication such as Synthroid, Levoxyl, Levothroid, and others;     ·insulin or an oral diabetes medicine such as glipizide (Glucotrol) or glyburide (Diabeta, Micronase);     ·tamoxifen (Nolvadex);     ·didanosine (Videx);     ·phenytoin (Dilantin) or ethotoin (Peganone);     ·carbamazepine (Tegretol);     ·phenobarbital (Solfoton, Luminal);     ·primidone (Mysoline); or     ·rifampin (Rifadin).

· A dosage adjustment or special monitoring may be required during treatment if you are taking any of the medicines listed above.

· Drugs other than those listed here may also interact with Ogen 2.5. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

 

Where can I get more information?

· Your pharmacist has additional information about Ogen 2.5 written for health professionals that you may read.

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