Panokase

 
Generic Name: pancrelipase (oral)

Brands: Cotazym, Cotazym-S, Creon 10, Creon 20, Creon 5, Ilozyme, Ku-Zyme, Pancrease, Pancrease MT 10, Pancrease MT 16, Pancrease MT 20, Pancrease MT 4, Ultrase, Ultrase MT 12, Ultrase MT 18, Ultrase MT 20, Viokase, Zymase

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What is the most important information I should know about Panokase?

· Take Panokase exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Taking Panokase properly is the most important factor in getting the maximum benefit of this medication.

· Do not inhale the powder inside the capsules or allow it to touch your skin. It may cause irritation, especially to your nose and lungs.

 

What is Panokase?

· Pancrelipase is a combination of three enzymes (proteins): lipase, protease, and amylase. These enzymes are produced naturally in the pancreas and are important in the digestion of fats, proteins, and sugars.

· Pancrelipase is used to replace these enzymes when the body does not have enough of its own. Pancrelipase reduces the pain associated with disorders of the pancreas. Conditions for which Panokase may be used include cystic fibrosis, chronic inflammation of the pancreas, and blockage of the pancreatic ducts. In addition, Panokase may be used following removal of the pancreas.

· Pancrelipase may also be used for purposes other than those listed in this medication guide.

 

What should I discuss with my healthcare provider before taking Panokase?

· Do not take Panokase without first talking to your doctor if you     ·are allergic to pork products;     ·have acute pancreatitis; or     ·have an acute worsening of a chronic pancreatic disease.

· You may not be able to take Panokase or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

· The Pancrease and Pancrease MT brands of Panokase are in the FDA pregnancy category B. This means that they are not expected to harm an unborn baby. Other brands of Panokase are in the FDA pregnancy category C or are not assigned an FDA pregnancy category. This means that it is not known whether they will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.

· It is also not known whether Panokase will harm a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding.

 

How should I take Panokase?

· Take Panokase exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

· Taking Panokase properly is the most important factor in getting the maximum benefit of this medication.

· Pancrelipase is taken before or during each meal or snack. Follow your doctor's specific instructions.

· Do not hold the tablets or capsule contents in your mouth. This may cause irritation of the inside of your mouth.

· Do not crush or chew the capsules or tablets. Swallow them whole. If swallowing is difficult, some formulations can be opened and sprinkled onto a soft food such as applesauce or pudding. The soft food should then be swallowed immediately without chewing and followed with a beverage to ensure swallowing. Ask your doctor about such formulations if you are having difficulty swallowing your pills.

· Do not inhale the powder inside the capsules or allow it to touch your skin. It may cause irritation, especially to your nose and lungs.

· Do not change brands of Panokase without first talking to your doctor or pharmacist. Some brands of Panokase are interchangeable while others are not. Your doctor and/or pharmacist know which brand/generic formulations may be substituted for another.

· Store Panokase at room temperature away from moisture and heat.

 

What happens if I miss a dose?

· Skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

 

What happens if I overdose?

· Seek emergency medical attention.

· Symptoms of a Panokase overdose are not known but may include diarrhea and stomach upset.

 

What should I avoid while taking Panokase?

· Follow any special diet recommendations made by your doctor while taking Panokase.

 

What are the possible side effects of Panokase?

· Stop taking Panokase and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

· Other, less serious side effects may also occur. Continue to take Panokase and notify your doctor if you experience     ·nausea or vomiting;     ·abdominal discomfort, pain, or cramping;     ·diarrhea or constipation;     ·greasy stools;     ·perianal irritation;     ·flatulence; or     ·irritation to the skin or lungs after coming in contact with capsule contents.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Panokase?

· Pancrelipase is not known to interact with any other medications. However, talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

 

Where can I get more information?

· Your pharmacist has more information about Panokase written for health professionals that you may read.

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