Reprexain

 
Generic Name: hydrocodone and ibuprofen

Brands: Vicoprofen

---

What is the most important information I should know about Reprexain?

· In rare cases, the use of ibuprofen has caused serious side effects. Contact your doctor immediately if you experience black, bloody or tarry stools; abdominal pain; bloody vomit; blurred vision or other visual problems; rash; sudden weight gain; or swelling.

· Do not take other prescription or over-the-counter medications that contain ibuprofen (Motrin, Advil, others) while taking Reprexain without first talking to your doctor.

· Never take more Reprexain than is prescribed for you. If your pain is not being adequately treated, talk to your doctor.

· Use caution when driving, operating machinery, or performing other hazardous activities. Reprexain may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities.

· Do not drink alcohol while taking Reprexain. Alcohol may increase drowsiness or dizziness. Alcohol may also increase the risk of dangerous stomach bleeding while taking this medication.

· Reprexain may cause constipation. Drink plenty of water (six to eight full glasses a day) to lessen this side effect. Increasing the amount of fiber in your diet may also help to alleviate constipation.

 

What is Reprexain?

· Hydrocodone (related to codeine) is in a class of drugs called narcotic analgesics. It is a pain reliever. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It relieves pain and decreases inflammation.

· Reprexain are used together for the short-term treatment of pain.

· Reprexain may also be used for purposes other than those listed in this medication guide.

 

What should I discuss with my healthcare provider before taking Reprexain?

· Hydrocodone is habit forming and should only be used under close supervision if you have an alcohol or drug addiction.

· Before taking this medication, tell your doctor if you have     ·kidney disease;     ·liver disease;     ·asthma;     ·urinary retention or an enlarged prostate;     ·hypothyroidism;     ·gallbladder disease;     ·a head injury;     ·Addison's disease;     ·an allergy to aspirin or any other NSAIDs;     ·an ulcer or bleeding in the stomach;     ·a bleeding or blood clotting disorder,     ·high blood pressure, heart disease, or fluid retention; or     ·a history of drug or alcohol addiction.

· You may not be able to take Reprexain, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

· This drug combination is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Ibuprofen should not be taken in late pregnancy because it may affect the baby's heart. Do not take this medication without first talking to your doctor if you are pregnant.

· It is not known whether Reprexain passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

· Reprexain has not been approved for use by children younger than 16 years of age.

 

How should I take Reprexain?

· Take Reprexain exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

· Take each dose with a full glass of water.

· Reprexain can be taken with food or milk to decrease stomach upset.

· Never take more Reprexain than is prescribed for you. If your pain is not being adequately treated, talk to your doctor.

· Reprexain may cause constipation. Drink plenty of water (six to eight full glasses a day) to lessen this side effect. Increasing the amount of fiber in your diet may also help to alleviate constipation.

· Do not share this medication with anyone else.

· Store Reprexain at room temperature away from moisture and heat.

 

What happens if I miss a dose?

· Take the missed dose as soon as you remember. Wait the prescribed amount of time before taking your next dose. Do not take a double dose of this medication.

 

What happens if I overdose?

· Seek emergency medical attention.

· Symptoms of a Reprexain overdose include slow breathing, dizziness, drowsiness, ringing in the ears, blurred vision, confusion, coma, and death.

 

What should I avoid while taking Reprexain?

· Use caution when driving, operating machinery, or performing other hazardous activities. Reprexain may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities.

· Do not drink alcohol while taking Reprexain. Alcohol may increase drowsiness or dizziness. Alcohol may also increase the risk of stomach bleeding while taking this medication.

· Do not take other prescription or over-the-counter medications that contain ibuprofen (Motrin, Advil, others) while taking Reprexain without first talking to your doctor.

· Drowsiness or dizziness caused by Reprexain may be increased by the effects of other drugs that cause drowsiness including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, muscle relaxants, and many others. Tell your doctor about all medicines that you are taking and do not take any medicine without first talking to your doctor.

 

What are the possible side effects of Reprexain?

· If you experience any of the following serious side effects, stop taking Reprexain and seek emergency medical attention or contact your doctor immediately:     ·an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);     ·slow or weak breathing;     ·yellowing of the skin or eyes;     ·unusual fatigue, bleeding, or bruising;     ·abdominal cramping, indigestion, or heartburn;     ·black, bloody, or tarry stools;     ·bloody vomit;     ·decreased hearing or ringing in the ears;     ·blurred vision or other visual problems; or     ·sudden weight gain (fluid retention).

· Other, less serious side effects may be more likely to occur. Continue to take Reprexain and talk to your doctor if you experience     ·constipation;     ·dry mouth, nausea, or decreased appetite;     ·dizziness, tiredness, or lightheadedness;     ·muscle twitches;     ·sweating;     ·itching; or     ·decreased urination.

· Reprexain is habit forming. Dependence may develop if it is taken for a prolonged period of time and withdrawal effects may occur if it is stopped suddenly after prolonged treatment.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Reprexain?

· Before taking Reprexain, tell your doctor if you are taking any of the following medicines:      ·another nonsteroidal anti-inflammatory drug (NSAID) such as ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Aleve, Anaprox), diclofenac (Voltaren, Cataflam), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin);     ·aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), choline salicylate, and magnesium salicylate;     ·a diuretic (water pill) such as hydrochlorothiazide (HCTZ, HydroDiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Thalitone), bumetanide (Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), spironolactone (Aldactone), and amiloride (Midamor);     ·an anticoagulant such as warfarin (Coumadin); or     ·lithium (Eskalith, Lithobid, others).

· You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

· Drowsiness or dizziness caused by Reprexain may be increased by the effects of other drugs that cause drowsiness including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, muscle relaxants, and many others. Tell your doctor about all medicines that you are taking and do not take any medicine without first talking to your doctor.

· Drugs other than those listed here may also interact with Reprexain. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

 

Where can I get more information?

· Your pharmacist has additional information about Reprexain written for health professionals that you may read.

Print this page