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Zonegran

 
Generic Name: zonisamide

Brands: Zonegran


What is the most important information I should know about Zonegran?

· Zonegran may cause drowsiness, dizziness, decreased concentration, vision problems, or poor coordination. Do not drive, operate dangerous machinery, or perform other hazardous activities until you know how Zonegran affects you. If you experience drowsiness, dizziness, decreased concentration, vision problems, or poor coordination, avoid these activities.

· Do not stop taking Zonegran without first talking to your doctor, even if you feel better. It is important to continue taking Zonegran to prevent the seizures from recurring. Stopping Zonegran suddenly may result in increased seizure frequency. If the medication needs to be stopped, your doctor may need to lower the dosage gradually.

· If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:     ·a rash;     ·fever, sore throat, sores in your mouth, or bruising easily (may be signs of a blood problem);     ·sudden back pain, stomach or abdominal pain, pain when urinating, bloody or dark urine (may be signs of a kidney stone);     ·decreased sweating or a rise in body temperature (especially in those under 17 years old);     ·depression;     ·severe drowsiness, difficulty concentrating, or coordination problems;     ·unusual thoughts; or     ·speech or language problems including difficulty finding words.

· Carry or wear a medical identification tag to let others know that you are taking this medicine in the case of an emergency.

 

What is Zonegran?

· Zonegran is used to control seizures. The exact way that Zonegran works is unknown.

· Zonegran may also be used for purposes other than those listed in this medication guide.

 

What should I discuss with my healthcare provider before taking Zonegran?

· Do not take Zonegran without first talking to your doctor if you have ever had an allergic reaction to a sulfa drug such as sulfamethoxazole (Gantanol, others); sulfisoxazole (Gantrisin, others); or sulfamethoxazole-trimethoprim (Bactrim, Bactrim DS, Septra, Septra DS, Cotrim, others). You may also have an allergic reaction to Zonegran.

· Before taking Zonegran, tell your doctor if you have liver or kidney disease. You may not be able to take Zonegran, or you may require a dosage adjustment or special monitoring during treatment.

· Zonegran is in the FDA pregnancy category C. This means that it is not known whether Zonegran will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

· It is not known whether Zonegran passes into breast milk. Do not take Zonegran without first talking to your doctor if you are breast-feeding a baby.

 

How should I take Zonegran?

· Take Zonegran exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

· Take each dose of Zonegran with a full glass of water. Also, drink 6 to 8 glasses of water a day to help prevent the formation of kidney stones.

· Swallow the Zonegran capsule whole. Do not crush, chew, or break them.

· Zonegran can be taken with or without food.

· It is important to take Zonegran regularly to get the most benefit.

· Do not stop taking Zonegran without first talking to your doctor, even if you feel better. It is important to continue taking Zonegran to prevent the seizures from recurring. Stopping Zonegran suddenly may result in increased seizure frequency. If the medication needs to be stopped, your doctor may need to lower the dosage gradually.

· If treatment with Zonegran is stopped for any reason, contact your doctor before restarting the medication. A lower dose may be needed to prevent side effects from occurring.

· Your doctor may want you to have blood tests or other medical evaluations during treatment with Zonegran to monitor progress and side effects.

· Carry or wear a medical identification tag to let others know that you are taking this medicine in the case of an emergency.

· Store Zonegran at room temperature away from moisture and heat.

 

What happens if I miss a dose?

· Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication.

 

What happens if I overdose?

· Seek emergency medical attention if an overdose is suspected.

· Symptoms of a Zonegran overdose are unknown but might include loss of consciousness, slow heart rate, low blood pressure, and slow breathing.

 

What should I avoid while taking Zonegran?

· Zonegran may cause drowsiness, dizziness, decreased concentration, vision problems, or poor coordination. Do not drive, operate dangerous machinery, or perform other hazardous activities until you know how Zonegran affects you. If you experience drowsiness, dizziness, decreased concentration, vision problems, or poor coordination, avoid these activities.

· Do not drink alcohol while taking Zonegran. Alcohol may increase drowsiness or dizziness caused by Zonegran. Alcohol may also increase the risk of seizures.

 

What are the possible side effects of Zonegran?

· If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:     ·an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);     ·a rash;     ·increasing frequency or worsening of seizures;     ·fever, sore throat, sores in your mouth, or bruising easily (may be signs of a blood problem);     ·sudden back pain, stomach or abdominal pain, pain when urinating, bloody or dark urine (may be signs of a kidney stone);     ·decreased sweating or a rise in body temperature (especially in those under 17 years old);     ·depression;     ·severe drowsiness, difficulty concentrating, or coordination problems;     ·unusual thoughts; or     ·speech or language problems including difficulty finding words.

· Other, less serious side effects may be more likely to occur. Continue to take Zonegran and talk to your doctor if you experience     ·dizziness;     ·mild drowsiness;     ·loss of appetite;     ·headache;     ·nausea; or     ·agitation or irritability.

· Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

 

What other drugs will affect Zonegran?

· Zonegran interacts with other drugs used to treat seizures. Before taking Zonegran, tell your doctor about all other medications you are taking. You may require a dosage adjustment or special monitoring during treatment if you are taking a combination of medications to treat seizures. Continue to take all medications prescribed to treat seizures exactly as directed.

· Zonegran may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if Zonegran is taken with any of these medications.

· Drugs other than those listed here may also interact with Zonegran. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

 

Where can I get more information?

· Your pharmacist has additional information about Zonegran written for health professionals that you may read.

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